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In-vivo Antidiabetic Activity of Methanolic Extract of Euphorbia hirta L

Received: 24 February 2017     Accepted: 6 June 2017     Published: 27 July 2017
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Abstract

Diabetes is a metabolic disorder which results from pancreatic beta cells dysfunction & insulin resistance and are characterized by hyperglycemia. The in-vivo anti-diabetic potential of E. hirta L. was also determined so as to justify the traditional usage of the plant in treating diabetes. The result of the present study confirmed that the methanolic extract of E. hirta possess significant anti-diabetic activity in-vivo, this shows that the plants has the potential for the development of drugs in combating diabetes.

Published in International Journal of Diabetes and Endocrinology (Volume 2, Issue 3)
DOI 10.11648/j.ijde.20170203.11
Page(s) 36-39
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2017. Published by Science Publishing Group

Keywords

Diabetes, Euphorbia hirta, Hyperglycemia, in-vivo

References
[1] Satyanarayana, U., Chakrapani, U., (2004). Biochemistry second edition. pp. 669.
[2] Conget, (2002). Diagnosis, classification and pathogenesis of diabetes mellitus. Rev. Esp. cardiol, 55(5): 528-35.
[3] Harbrone, S. B., Baxter, H., (1995). Phytochemical Dictionary. A handbook of bioactive compounds from plants Taylor and Francis, London.
[4] Sikarwar, M. S., Patil, M. B., Kokate, C. K., Sharma, S., and Bhat, V., (2009). Antidiabetic activity of Neriumindicum leaf extract in alloxan-induced diabetic rats. Journal of young pharmacist. 1(4): 330-335.
[5] Arunachalam. K., Parimelazhagan, T., (2012). Antioxidant properties from methanol extract of Ficustalboti bark on diabetic rats induced by Streptozotocin. Asian pac. Journal of Reproduction. 3(2), 97-105.
[6] Matthew, O., Olusola, L., and Oluwole, A. M., (2012). Preliminary study of Hypoglycaemic and Hypolipidemic activity of aqueous root extract of Ricinus Communis in Alloxan-Induced Diabetic Rats. Journal of Physiology and Pharmacology Advances. 2(10): 354-359.
[7] Ashish, B., and swapinal, G., (2011). Hypoglycaemic effect of polyherbal formulation in Alloxan Induced Diabetic Rats. Pharmacology online. 3, 764-773.
[8] Sabu, M. C., and Kuttan, R., (2002). Anti-diabetic activity of medicinal plants and its relationship with their antioxidant property. J. Ethanopharmacol., 81: 155-160.
[9] O. H. Osmani, D. S. Sekar, K. L. Senthil Kumar, R. K. Sahu, A. Roy, ( 2009) Biomedical and Pharmacological Journal, 2(2): 339-343.
[10] M. B. Krishna, S. Nammi, M. K. Kota, R. V. Krishna Rao, N. Koteswara Rao, A. Annapurna, (2004) J. Ethnopharmacol, 91: 95-98.
[11] U. Sharma, R. K. Sahu, A. Roy, D. K. Golwala, Journal of Young Pharmacists 2010, 2(3): 255-260. [4] D. Loew, M. Kaszkin, Phytother. Res., 2002, 16: 705-711.
[12] El-Mahmood MA. (2009). Antibacterial activity of crude extracts of Euphorbia hirta against some bacteria associated with enteric infections; 3(7): 498-505.
[13] Kumar S, Malhotra R, Kumar D. (2010) Euphorbia hirta L: Its chemistry, traditional and medicinal uses, and pharmacological activities; 4: 58- 61.
[14] Anozie VL. (1981) God’s healing power in plants. Clin Pharm Herb Medium; 7: 23-25.
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  • APA Style

    Sangeeta Devi, Muneesh Kumar. (2017). In-vivo Antidiabetic Activity of Methanolic Extract of Euphorbia hirta L. International Journal of Diabetes and Endocrinology, 2(3), 36-39. https://doi.org/10.11648/j.ijde.20170203.11

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    ACS Style

    Sangeeta Devi; Muneesh Kumar. In-vivo Antidiabetic Activity of Methanolic Extract of Euphorbia hirta L. Int. J. Diabetes Endocrinol. 2017, 2(3), 36-39. doi: 10.11648/j.ijde.20170203.11

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    AMA Style

    Sangeeta Devi, Muneesh Kumar. In-vivo Antidiabetic Activity of Methanolic Extract of Euphorbia hirta L. Int J Diabetes Endocrinol. 2017;2(3):36-39. doi: 10.11648/j.ijde.20170203.11

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  • @article{10.11648/j.ijde.20170203.11,
      author = {Sangeeta Devi and Muneesh Kumar},
      title = {In-vivo Antidiabetic Activity of Methanolic Extract of Euphorbia hirta L},
      journal = {International Journal of Diabetes and Endocrinology},
      volume = {2},
      number = {3},
      pages = {36-39},
      doi = {10.11648/j.ijde.20170203.11},
      url = {https://doi.org/10.11648/j.ijde.20170203.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20170203.11},
      abstract = {Diabetes is a metabolic disorder which results from pancreatic beta cells dysfunction & insulin resistance and are characterized by hyperglycemia. The in-vivo anti-diabetic potential of E. hirta L. was also determined so as to justify the traditional usage of the plant in treating diabetes. The result of the present study confirmed that the methanolic extract of E. hirta possess significant anti-diabetic activity in-vivo, this shows that the plants has the potential for the development of drugs in combating diabetes.},
     year = {2017}
    }
    

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  • TY  - JOUR
    T1  - In-vivo Antidiabetic Activity of Methanolic Extract of Euphorbia hirta L
    AU  - Sangeeta Devi
    AU  - Muneesh Kumar
    Y1  - 2017/07/27
    PY  - 2017
    N1  - https://doi.org/10.11648/j.ijde.20170203.11
    DO  - 10.11648/j.ijde.20170203.11
    T2  - International Journal of Diabetes and Endocrinology
    JF  - International Journal of Diabetes and Endocrinology
    JO  - International Journal of Diabetes and Endocrinology
    SP  - 36
    EP  - 39
    PB  - Science Publishing Group
    SN  - 2640-1371
    UR  - https://doi.org/10.11648/j.ijde.20170203.11
    AB  - Diabetes is a metabolic disorder which results from pancreatic beta cells dysfunction & insulin resistance and are characterized by hyperglycemia. The in-vivo anti-diabetic potential of E. hirta L. was also determined so as to justify the traditional usage of the plant in treating diabetes. The result of the present study confirmed that the methanolic extract of E. hirta possess significant anti-diabetic activity in-vivo, this shows that the plants has the potential for the development of drugs in combating diabetes.
    VL  - 2
    IS  - 3
    ER  - 

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Author Information
  • Department of Botany Govt. Degree College Doda, University of Jammu, Jammu and Kashmir, India

  • Department of Zoology Govt. Degree College Doda, University of Jammu, Jammu and Kashmir, India

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