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Electrolyte Levels Analysis on Diabetes Mellitus Patients in Noongan Regional General Hospital, North Sulawesi, Indonesia

Received: 16 October 2020     Accepted: 16 November 2020     Published: 19 November 2020
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Abstract

Diabetes mellitus is a metabolic disease characterized by hyperglycemia caused by defects in insulin secretion, insulin action, or both, that affect the action of insulin on the target tissue. North Sulawesi is in the top 5 of 34 provinces in Indonesia with the highest prevalence of diabetes mellitus, based on the results of the 2018 Basic Health Research. The relationship between blood glucose and electrolytes is very complex, so there are still few studies looking for the relationship between the two in diabetes mellitus patients. This study aimed to find out the association between electrolytes levels (serum sodium, potassium, chloride, and magnesium) and fasting blood glucose in type 2 diabetes mellitus patients. This cross-sectional study was conducted in April-September 2020 at Noongan Regional Hospital, North Sulawesi, Indonesia. Demographic data including age, sex, symptoms, and oral anti-diabetic medication/insulin administration were collected, and then physical examination including body mass index was carried out. The Kolmogorov-Smirnov and Spearman Rank tests were used for statistical analysis. There is an inverse correlation between fasting blood glucose and serum sodium, chloride, and magnesium, but not significant. As for potassium, there is a direct correlation, but also not significant. In conclusion, only potassium has a positive correlation with fasting blood glucose, while other electrolytes have a negative correlation, however all of correlations are not significant.

Published in International Journal of Diabetes and Endocrinology (Volume 5, Issue 4)
DOI 10.11648/j.ijde.20200504.11
Page(s) 54-60
Creative Commons

This is an Open Access article, distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution and reproduction in any medium or format, provided the original work is properly cited.

Copyright

Copyright © The Author(s), 2020. Published by Science Publishing Group

Keywords

Diabetes Mellitus, Electrolyte, Blood Glucose

References
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[7] Valarmathi, A., Sastri, L. Evaluation of Electrolytes Level Imbalance as a Risk Factor for Chronic Complications in Diabetic Patients. Sch J App Med Sci. 2017; Vol. 5 (7E): p. 2934-2936.
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[9] Datchinamoorthi, S., Vanaja, R., Rajagopalan, B. Evaluation of Serum Electrolytes in Type II Diabetes Mellitus. Int J Pharm Sci Rev Res. 2016; Vol. 40 (1): p. 251-253.
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[13] Dedinská, I., Graňák, K., Vnučák, M., Skálová, P., Kováčiková, L., Laca, Ľ., et al. Role of Sex In Post-Transplant Diabetes Mellitus Development: Are Men and Women Equal? J Diabetes Complications. 2019; Vol. 33 (4): p. 315-322.
[14] Casqueiro, J., Casqueiro, J., Alves, C. Infection in Patients with Diabetes Mellitus: A Review of Pathogenesis. Indian J Endocrinol Metab. 2012; Vol. 16 (1): p. S27-S36.
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Cite This Article
  • APA Style

    Diana Shintawati Purwanto, Yanti Meilen Mewo, Edmond Leonard Jim, Richardo Jordan Laloan, Hessyani Patrisia Theodora Raranta, et al. (2020). Electrolyte Levels Analysis on Diabetes Mellitus Patients in Noongan Regional General Hospital, North Sulawesi, Indonesia. International Journal of Diabetes and Endocrinology, 5(4), 54-60. https://doi.org/10.11648/j.ijde.20200504.11

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    ACS Style

    Diana Shintawati Purwanto; Yanti Meilen Mewo; Edmond Leonard Jim; Richardo Jordan Laloan; Hessyani Patrisia Theodora Raranta, et al. Electrolyte Levels Analysis on Diabetes Mellitus Patients in Noongan Regional General Hospital, North Sulawesi, Indonesia. Int. J. Diabetes Endocrinol. 2020, 5(4), 54-60. doi: 10.11648/j.ijde.20200504.11

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    AMA Style

    Diana Shintawati Purwanto, Yanti Meilen Mewo, Edmond Leonard Jim, Richardo Jordan Laloan, Hessyani Patrisia Theodora Raranta, et al. Electrolyte Levels Analysis on Diabetes Mellitus Patients in Noongan Regional General Hospital, North Sulawesi, Indonesia. Int J Diabetes Endocrinol. 2020;5(4):54-60. doi: 10.11648/j.ijde.20200504.11

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  • @article{10.11648/j.ijde.20200504.11,
      author = {Diana Shintawati Purwanto and Yanti Meilen Mewo and Edmond Leonard Jim and Richardo Jordan Laloan and Hessyani Patrisia Theodora Raranta and Billy Johnson Kepel},
      title = {Electrolyte Levels Analysis on Diabetes Mellitus Patients in Noongan Regional General Hospital, North Sulawesi, Indonesia},
      journal = {International Journal of Diabetes and Endocrinology},
      volume = {5},
      number = {4},
      pages = {54-60},
      doi = {10.11648/j.ijde.20200504.11},
      url = {https://doi.org/10.11648/j.ijde.20200504.11},
      eprint = {https://article.sciencepublishinggroup.com/pdf/10.11648.j.ijde.20200504.11},
      abstract = {Diabetes mellitus is a metabolic disease characterized by hyperglycemia caused by defects in insulin secretion, insulin action, or both, that affect the action of insulin on the target tissue. North Sulawesi is in the top 5 of 34 provinces in Indonesia with the highest prevalence of diabetes mellitus, based on the results of the 2018 Basic Health Research. The relationship between blood glucose and electrolytes is very complex, so there are still few studies looking for the relationship between the two in diabetes mellitus patients. This study aimed to find out the association between electrolytes levels (serum sodium, potassium, chloride, and magnesium) and fasting blood glucose in type 2 diabetes mellitus patients. This cross-sectional study was conducted in April-September 2020 at Noongan Regional Hospital, North Sulawesi, Indonesia. Demographic data including age, sex, symptoms, and oral anti-diabetic medication/insulin administration were collected, and then physical examination including body mass index was carried out. The Kolmogorov-Smirnov and Spearman Rank tests were used for statistical analysis. There is an inverse correlation between fasting blood glucose and serum sodium, chloride, and magnesium, but not significant. As for potassium, there is a direct correlation, but also not significant. In conclusion, only potassium has a positive correlation with fasting blood glucose, while other electrolytes have a negative correlation, however all of correlations are not significant.},
     year = {2020}
    }
    

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  • TY  - JOUR
    T1  - Electrolyte Levels Analysis on Diabetes Mellitus Patients in Noongan Regional General Hospital, North Sulawesi, Indonesia
    AU  - Diana Shintawati Purwanto
    AU  - Yanti Meilen Mewo
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    JF  - International Journal of Diabetes and Endocrinology
    JO  - International Journal of Diabetes and Endocrinology
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    PB  - Science Publishing Group
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    UR  - https://doi.org/10.11648/j.ijde.20200504.11
    AB  - Diabetes mellitus is a metabolic disease characterized by hyperglycemia caused by defects in insulin secretion, insulin action, or both, that affect the action of insulin on the target tissue. North Sulawesi is in the top 5 of 34 provinces in Indonesia with the highest prevalence of diabetes mellitus, based on the results of the 2018 Basic Health Research. The relationship between blood glucose and electrolytes is very complex, so there are still few studies looking for the relationship between the two in diabetes mellitus patients. This study aimed to find out the association between electrolytes levels (serum sodium, potassium, chloride, and magnesium) and fasting blood glucose in type 2 diabetes mellitus patients. This cross-sectional study was conducted in April-September 2020 at Noongan Regional Hospital, North Sulawesi, Indonesia. Demographic data including age, sex, symptoms, and oral anti-diabetic medication/insulin administration were collected, and then physical examination including body mass index was carried out. The Kolmogorov-Smirnov and Spearman Rank tests were used for statistical analysis. There is an inverse correlation between fasting blood glucose and serum sodium, chloride, and magnesium, but not significant. As for potassium, there is a direct correlation, but also not significant. In conclusion, only potassium has a positive correlation with fasting blood glucose, while other electrolytes have a negative correlation, however all of correlations are not significant.
    VL  - 5
    IS  - 4
    ER  - 

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Author Information
  • Department of Biochemistry, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia

  • Department of Biochemistry, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia

  • Department of Cardiovascular Medicine, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia

  • Clinical Clerkship Program, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia

  • Department of Clinical Laboratory, R. D Kandou Central General Hospital, Manado, Indonesia

  • Department of Chemistry, Faculty of Medicine, Sam Ratulangi University, Manado, Indonesia

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